Pharmacological effects of Ginsenoside Rh1
- Anti-allergy effect
- Anti-inflammation effect
- Cytotoxic effects on various cancer cell lines
- Prevention of tumor cell proliferation and differentiation
- Inhibition of liver disease promotion
- Prevention of blood platelet coagulation
Clinical papers on Ginsenoside Rh1 (www.pubmed.com – U.S. National Library of Medicine, National Institute of Health
- Control of phenotypic expression of cultured B16 melanoma cells by plant glycosides. Cancer Res. 45: 2781-2784 (1985)
- Plant-glycoside modulation of cell surface related to control of differentiation in cultured B16 melanoma cells. Cancer Res. 47: 3863-3867 (1987)
- Immunocytochemical localization of rH1 sodium channel in adult rat heart atria and ventricle. Presence in terminal intercalated disks. Circulation. 1996 Dec 15; 94(12):3083-6.
- Anti-invasive activity of ginsenoside Rh1 and Rh2 in the HT1080 cells. J. Ginseng Res. 22: 216-221 (1998)
- Pharmacological properties of a new aziridinylbenzoquinone, RH1 (2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone), in mice – cytochrome b5 reductase in human tumour cells. Biochemical Pharmacology, Volume 59,Number 7, 1 April 2000, pp. 831-837(7)
- A ginsenoside-Rh1, a component of ginseng saponin, activates estrogen receptor in human breast carcinoma MCF-7 cells. J. Steroid Biochem Mol Biol. 2003 Mar; 84(4):463-8.
- Ginsenoside Rh1 possesses antiallergic and anti-inflammatory activities. Int. Arch. Allergy Immunol. 133: 113-120 (2004)
- RH1 Induces Cellular Damage in an NAD(P)H:Quinone. Oxidoreductase 1-Dependent Manner: Relationship between DNA Cross-linking, Cell Cycle Perturbations, and Apoptosis THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, Vol. 313, No. 2
- Isolation of Ginsenoside Rh1 and Compound K from Fermented Ginseng and Efficacy Assessment on Systemic Anaphylactic Shock. Food Sci.Biotechnol.Vol.17,No.4,pp.000~000(2008)